bsm-51631M [Primary Antibody]
TPX2 Monoclonal Antibody
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Host: Mouse

Target Protein: TPX2

Clonality: Monoclonal

Entrez Gene: 22974

Swiss Prot: Q9ULW0

Source: Recombinant human TPX2 between 1-531 amino acids.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background:

Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.

Size: 100µL

Concentration: 0.5ug/ul

Applications: WB(WB=1:500-2000)

Predicted Molecular Weight: 86


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with TPX2 monoclonal antibody, unconjugated (bsm-51631M) at 1:800 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.