bsm-51664M [Primary Antibody]
RANBP9 Monoclonal Antibody
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Host: Mouse

Target Protein: RANBP9

Clonality: Monoclonal

Entrez Gene: 10048

Swiss Prot: Q96S59

Source: Recombinant human RANBP9 between 1-388 amino acids.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background:

May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.

Size: 100uL

Concentration: 0.5ug/ul

Applications: WB(WB=1:500-4000)
IHC-P(IHC-P=1:25)
IHC-F(IHC-F=1:25)
IF(IF=1:25)

Predicted Molecular Weight: 78


Predicted Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Paraformaldehyde-fixed, paraffin embedded Human heart; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with RANBP9 Monoclonal Antibody, Unconjugated (bsm-51664M) at 1:25 overnight at 4°C, DAB staining.