bsm-51700M

DATASHEET

Host: Mouse

Target Protein: BMP11

Clonality: Monoclonal

Entrez Gene: 10220

Swiss Prot: O95390

Source: Recombinant human GDF11.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background:

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.

Size: 100ul

Concentration: Lot Dependent

Applications: WB(WB=1:500-2000)

Predicted Molecular Weight: Dec-43

Cross Reactive Species: Recombinant protein

Predicted Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.