bsm-51738M [Primary Antibody]
PURB Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: PURB

Clonality: Monoclonal

Entrez Gene: 5814

Swiss Prot: Q96QR8

Source: Recombinant human PURB.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs.

Size: 100ul

Concentration: 0.5ug/ul

Applications: WB=1:1000-4000，

Predicted Molecular Weight: 33


Predicted Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: Jurkat cell lysates; Lane 2: Hela cell lysates; Lane 3: NCI-H460 cell lysates; Lane 4: HepG2 cell lysates; Lane 5: Mcf-7 cell lysates; Lane 6: NIH/3T3 cell lysates probed with PURB Monoclonal Antibody, Unconjugated (bsm-51738M) at 1:8000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.