DATASHEET
Host:
Mouse
Target Protein:
SULT2B1
Clonality:
Monoclonal
Entrez Gene:
6820
Swiss Prot:
O00204
Source:
Recombinant human SULT2B1.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
Catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol.
VALIDATION IMAGES
Lane 1: MCF-7 cell lysates; Lane 2: MDA-MB-468 cell lysates probed with SULT2B1 Monoclonal Antibody, Unconjugated (bsm-51745M) at 1:8000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Lane 1: Mcf-7 cell lysates probed with SULT2B1 Monoclonal Antibody, Unconjugated (bsm-51745M) at 1:8000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.