bsm-51750M [Primary Antibody]
Glucocorticoid receptor Monoclonal Antibody
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Host: Mouse

Target Protein: Glucocorticoid receptor

Clonality: Monoclonal

Entrez Gene: 2908

Swiss Prot: P04150

Source: Recombinant human Glucocorticoid receptor.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background:

Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.

Size: 100ul

Concentration: 0.5ug/ul

Applications: WB=1:500-2000，

Predicted Molecular Weight: 85


Cross Reactive Species: Human
Hamster

Predicted Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: Hela cell lysates; Lane 2: A549 cell lysates; Lane 3: CCRF-CEM cell lysates; Lane 4: CHO cell lysates probed with Glucocorticoid receptor Monoclonal Antibody, Unconjugated (bsm-51750M) at 1:2000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.


Lane 1: DU145 cell lysates; Lane 2: U-251MG cell lysates probed with Glucocorticoid receptor Monoclonal Antibody, Unconjugated (bsm-51750M) at 1:2000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.