bsm-52012R-HRP

DATASHEET

Host: Rabbit

Target Protein: ALAS1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 211

Swiss Prot: P13196

Source: recombinant human Alas1 C-terminal 200aa

Purification: purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]

Conjugation: HRP

Excitation/ Emission: N/A

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:500-2000)
ICC/IF(1:50-200)
Flow-Cyt(1:50-100)

Predicted Molecular Weight: 65 kDa

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.