Target Protein: ARF6
Entrez Gene: 382
Swiss Prot: P62330
Source: Recombinant human ARF6 protein, full length.
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition: Store at -20°C for 12 months.
Background: GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.