DATASHEET
Host:
Rabbit
Target Protein:
Aurora B
Clonality:
Recombinant
Isotype:
IgG
Entrez Gene:
9212
Swiss Prot:
Q96GD4
Source:
Recombinant human Aurora B protein, around N-terminal 150aa.
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
Mahogany (MG), originally identified as a protein involved in pigmentation, acts in conjunction with melanocortin receptors to suppress diet-induced obesity. Mahogany contains a single transmembrane domain, and it is expressed in a broad range of tissues, including the hypothalamus and pigment cells. Mutations within the mahogany gene were shown to rescue agouti-lethal-yellow mutant mice from obesity. The extracellular domain of mouse mahogany is the ortholog of the human protein attractin. Attractin (also designated DPPT-L) is a human serum glycoprotein and is a member of the CUB family of cell adhesion and guidance proteins. Attractin is expressed on activated T cells and is released from the cells 48 to 72 hours after activation.
Conjugation:
PerCP-Cy7
Excitation/ Emission:
482nm/780nm
Size:
100uL
Concentration:
Lot dependent
Applications:
WB(1:300-5000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF
ICC/IF(1:50-100)
Human
For research use only. Not intended for diagnostic or therapeutic use.