bsm-52085R-FITC

DATASHEET

Host: Rabbit

Target Protein: HDAC4

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 9759

Swiss Prot: P56524

Source: Recombinant human HDAC4 protein, around C-terminal 100aa.

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:300-5000)

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.