bsm-52092R-Biotin

DATASHEET

Host: Rabbit

Target Protein: HIF-1 beta

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 405

Swiss Prot: P27540

Source: Recombinant human HIF-1 beta protein, around 600-700aa.

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100µL

Concentration: Lot dependent

Applications: WB(WB(1:500-2000))
IHC-P(IHC-P(1:50-200))
IHC-F(IHC-F(1:50-200))

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.