bsm-52202R-BF405

DATASHEET

Host: Rabbit

Target Protein: SIRT1 (Thr530)

Modification Site: T530

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 23411

Swiss Prot: Q96EB6

Source: KLH conjugated synthesised phosphopeptide derived from human SIRT1 around the phosphorylation site of Thr530

Purification: purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

Conjugation: AbBy Fluor-405

Excitation/ Emission: 401nm/421nm

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:500-1000)

Predicted Molecular Weight: 81 kDa

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.