bsm-52219M-PerCP [Conjugated Primary Antibody]
PIK3R1 Monoclonal Antibody, PerCP Conjugated
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Host: Mouse

Target Protein: PIK3R1

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 5295

Swiss Prot: P27986

Source: Recombinant human PI3-kinase p85 subunit alpha protein, around 600-700aa.

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Conjugation: PerCP

Excitation/ Emission: 482nm/677nm

Size: 100µL

Concentration: 1ug/ul

Applications: WB(1:500-2000)
IF(1:100-500)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Di Wu. et al. Alpinetin prevents inflammatory responses in OVA-induced allergic asthma through modulating PI3K/AKT/NF-B and HO-1 signaling pathways in mice. Int Immunopharmacol. 2020 Dec;89:107073Read more>>
  • Hanpeng Wu. et al. The release of FB1-induced heterophil extracellular traps in chicken is dependent on autophagy and glycolysis. POULTRY SCIENCE. 2023 Jan;:102511Read more>>
VALIDATION IMAGES