bsm-52270R-Cy7

DATASHEET

Host: Rabbit

Target Protein: DUSP6

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 1848

Swiss Prot: Q16828

Source: Recombinant protein within Human DUSP6 aa 1-350

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Inactivates MAP kinases. Has a specificity for the ERK family (PubMed:9858808). Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity). Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain (By similarity).

Conjugation: Cy7

Excitation/ Emission: 743nm/767nm

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:300-5000)
IF(1:50-200)
Flow-Cyt(1ug/Test)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.