bsm-52368R-Biotin [Conjugated Primary Antibody]
BDNF Recombinant Antibody, Biotin Conjugated
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Host: Rabbit

Target Protein: BDNF

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 627

Swiss Prot: P23560

Source: Recombinant human BDNF between 1 to 100 amino acids

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100µL

Concentration: 1mg/ml

Applications: WB(1:300-5000)
IHC-P(1:20-100)
IHC-F(1:200-400)

Predicted Molecular Weight: 28 kDa


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Pallavi Gurung. et al. Euonymus alatus Twig Extract Protects against Scopolamine-Induced Changes in Brain and Brain-Derived Cells via Cholinergic and BDNF Pathways. NUTRIENTS. 2023 Jan;15(1):128Read more>>
  • Xiaoyu Ma. et al. Multifunctional injectable hydrogel promotes functional recovery after stroke by modulating microglial polarization, angiogenesis and neuroplasticity. CHEM ENG J. 2023 May;464:14252Read more>>
  • Pallavi Gurung. et al. Euonymus alatus Leaf Extract Attenuates Effects of Aging on Oxidative Stress, Neuroinflammation, and Cognitive Impairment. ANTIOXIDANTS-BASEL. 2024 Apr;13(4):433Read more>>
  • Ying Yang. et al. Arjunolic acid ameliorates lipopolysaccharide-induced depressive behavior by inhibiting neuroinflammation via microglial SIRT1/AMPK/Notch1 signaling pathway. J ETHNOPHARMACOL. 2024 Aug;330:118225Read more>>
VALIDATION IMAGES