bsm-52373R-Biotin

DATASHEET

Host: Rabbit

Target Protein: MMP14

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 4323

Swiss Prot: P50281

Source: Recombinant human MMP14 between 150 to 250 amino acids

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:500-2000)
IHC-P(1:50-100)
IHC-F(1:100-500)
IP(1-2ug)

Predicted Molecular Weight: 65 kDa

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.