bsm-52375R-Cy3

DATASHEET

Host: Rabbit

Target Protein: CD86

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 942

Swiss Prot: P42081

Source: Recombinant human CD86 between 1 to 200 amino acids

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Store at -20°C for 12 months.

Background:

Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100uL, 20uL

Concentration: Lot Dependent

Applications: WB(1:100-200)
Flow-Cyt(1:500-2000)
ICC/IF(1:100-200)

Predicted Molecular Weight: 70 kDa

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.