bsm-52381R

DATASHEET

Host: Rabbit

Target Protein: Apaf-1

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 317

Swiss Prot: O14727

Source: Recombinant human Apaf-1 between 1 to 300 amino acids

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Size: 100uL

Concentration: Lot Dependent

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IF(ICC)(1:50-200)
IHC(1:50-200)

Predicted Molecular Weight: 141 kDa

Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.