bsm-52495R [Primary Antibody]
Estrogen Related Receptor alpha (1H13) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Estrogen Related Receptor alpha

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 2101

Swiss Prot: P11474

Source: Recombinant protein within Human Estrogen Related Receptor alpha aa 1-100

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.

Size: 100ul

Concentration: 1ug/ul

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Flow cytometric analysis of HeLa cells with Estrogen Related Receptor alpha (1H13) Monoclonal Antibody (bsm-52495R) at 1:50 dilution (red) compared with an unlabeled control (cells without incubation with primary antibody; black).


MCF-7 cell lysate probed with Estrogen Related Receptor alpha (1H13) Monoclonal Antibody (bsm-52495R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C