bsm-52505R-RBITC

DATASHEET

Host: Rabbit

Target Protein: PRNP

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 5621

Swiss Prot: P04156

Source: KLH conjugated synthetic peptide derived from PRNP

Purification: purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

Conjugation: RBITC

Excitation/ Emission: 570nm/595nm

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:500-2000)
IHC-F(1:50-200)
IHC-P(1:50-200)
IF(1:50-200)
ICC/IF(1:50-200)
Flow-Cyt(1:50-100)

Predicted Molecular Weight: 25 kDa

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.