bsm-52561R [Primary Antibody]
Junctional Adhesion Molecule 1 (7E1F) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: F11R

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 50848

Swiss Prot: Q9Y624

Source: Human Junctional Adhesion Molecule 1 between 28-241 amino acids

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 33


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: Hela Cells; Lane 2: Human liver; Probed with Junctional Adhesion Molecule 1 (7E1F) Monoclonal Antibody (bsm-52561R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.


Paraformaldehyde-fixed and paraffin-embedded Mouse liver tissue incubated with Junctional Adhesion Molecule 1 (7E1F) Monoclonal Antibody (bsm-52561R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.


Paraformaldehyde-fixed and paraffin-embedded Mouse Brain tissue incubated with Junctional Adhesion Molecule 1 (7E1F) Monoclonal Antibody (bsm-52561R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.


Paraformaldehyde-fixed and paraffin-embedded Mouse Liver tissue incubated with Junctional Adhesion Molecule 1 (7E1F) Monoclonal Antibody (bsm-52561R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.