bsm-52614R-BF750 [Conjugated Primary Antibody]
ACE2 Recombinant Antibody, AbBy Fluor-750 Conjugated
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Host: Rabbit

Target Protein: ACE2

Immunogen Range: 180-240/805


Clonality: Recombinant

Isotype: IgG

Entrez Gene: 59272

Swiss Prot: Q9BYF1

Source: C terminal human Angiotensin Converting Enzyme 2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

Conjugation: AbBy Fluor-750

Excitation/ Emission: 749nm/775nm

Size: 100µL

Concentration: Lot dependent

Applications: WB(WB(1:500-2000))
IF(IHC-P)(IF(IHC-P)(1:100-500))
IF(ICC)(IF(ICC)(1:50-200))

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Endika Prieto-Fernndez. et al. Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate. Emerg Microbes Infec. 2021;10(1):1065-1076Read more>>
VALIDATION IMAGES