bsm-52615R [Primary Antibody]
Glycogen synthase (1A8) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Glycogen synthase

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 2997

Swiss Prot: P13807

Source: Recombinant human Glycogen synthase between 700 to 800 amino acids

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70% identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.

Size: 100ul

Concentration: 1ug/ul

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Flow cytometric analysis of 293 cells with Glycogen synthase (1A8) Monoclonal Antibody (bsm-52615R) at 1:50 dilution (red) compared with an unlabeled control (cells without incubation with primary antibody; black).


Hela cells probed with Glycogen synthase (1A8) Monoclonal Antibody (bsm-52615R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.