DATASHEET
Host:
Rabbit
Target Protein:
LSP1
Clonality:
Monoclonal
Isotype:
IgG
Entrez Gene:
4046
Swiss Prot:
P33241
Source:
C terminal Human LSP1
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C for 12 months.
Background:
May play a role in mediating neutrophil activation and chemotaxis. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
VALIDATION IMAGES
Daudi cell lysate probed with LSP1 (9H10) Monoclonal Antibody (bsm-52643R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
Paraformaldehyde-fixed and paraffin-embedded Human tonsil tissue incubated with LSP1 (9H10) Monoclonal Antibody (bsm-52643R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.