bsm-52652R-BF555

DATASHEET

Host: Rabbit

Target Protein: GRM1

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 2890

Swiss Prot: P42261

Source: Recombinant protein within Human Glutamate Receptor 1 aa 850 to the C-terminus

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Conjugation: AbBy Fluor-555

Excitation/ Emission: 553nm/568nm

Size: 100µL

Concentration: Lot dependent

Applications: IF(IHC-P)(IF(IHC-P)(1:100-500))

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.