DATASHEET
Host:
Rabbit
Target Protein:
NQO1
Clonality:
Monoclonal
Isotype:
IgG
Entrez Gene:
1728
Swiss Prot:
P15559
Source:
Full length protein
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
PRODUCT SPECIFIC PUBLICATIONS
- Zeba Farooqui . et al. Nrf2 inhibition induces oxidative stress, renal inflammation and hypertension in mice. Clin Exp Hypertens. 2021;43(2):175-18Read more>>
VALIDATION IMAGES
Flow cytometric analysis of Hela cells with NQO1 (8T5) Monoclonal Antibody (bsm-52830R) at a 1:50 dilution (red) compared with an unlabeled control (cells without incubation with primary antibody; black).
Lane 1: SH-SY-5Y lysates; Lane 2: Mouse kidney lysates; Line 3: Raji lysates ;Probed with NQO1 (8T5) Monoclonal Antibody (bsm-52830R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.