bsm-52833R

DATASHEET

Host: Rabbit

Target Protein: Bcl-2

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 596

Swiss Prot: P10415

Source: KLH conjugated synthetic peptide derived from human Bcl-2

Purification: purified by Protein A.

Storage Buffer: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Size: 100ul

Concentration: 1mg/ml

Applications: WB(1:2000-10000)
IHC-P(1:500-2000)
IHC-F(1:500-2000)
IF(1:200-1000)
ELISA(1:5000-20000)

Predicted Molecular Weight: 26 kDa

Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Chicken

For research use only. Not intended for diagnostic or therapeutic use.