bsm-52898R
[Primary Antibody]
XBP1 (2C5) Monoclonal Antibody
DATASHEET
Host: Rabbit
Target Protein: XBP1
Clonality: Monoclonal
Isotype: IgG
Entrez Gene: 7494
Swiss Prot: P17861
Source: Human XBP1 aa 100-200
Purification: Purified by Protein A.
Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C for 12 months.
Background:
Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.
Size: 100ul
Concentration: 1ug/ul
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Flow cytometric analysis of 293T cells with XBP1 (2C5) Monoclonal Antibody (bsm-52898R) at a 1:50 dilution (red) compared with an unlabeled control (cells without incubation with primary antibody; black).
Lane 1: HepG2 cells lysates; Lane 2: 293T brain cells lysates; Probed with XBP1 (2C5) Monoclonal Antibody (bsm-52898R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.