bsm-52912R-APC-Cy5.5

DATASHEET

Host: Rabbit

Target Protein: CD41/ITGA2B

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 3674

Swiss Prot: P08514

Source: A synthesized peptide derived from human Integrin alpha 2b

Purification: purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Conjugation: APC-Cy5.5

Excitation/ Emission: 650nm/694nm

Size: 100ul

Concentration: 1mg/ml

Applications: IHC-F(1:100-500)
IHC-P(1:100-500)
IF(1:100-500)

Predicted Molecular Weight: 113 kDa

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.