DATASHEET
Host:
Rabbit
Target Protein:
mGluR1
Clonality:
Monoclonal
Isotype:
IgG
Entrez Gene:
2911
Swiss Prot:
Q13255
Source:
Human mGluR1 between 100-300 amino acids
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C for 12 months.
Background:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.
VALIDATION IMAGES
Rat brain cells lysates probed with mGluR1 (2C1) Monoclonal Antibody (bsm-52959R) at 1:500 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
Paraformaldehyde-fixed and paraffin-embedded Mouse brain tissue incubated with mGluR1 (2C1) Monoclonal Antibody (bsm-52959R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
Paraformaldehyde-fixed and paraffin-embedded Mouse kidney tissue incubated with mGluR1 (2C1) Monoclonal Antibody (bsm-52959R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.