bsm-54021R-BF488

DATASHEET

Host: Rabbit

Target Protein: Annexin A2 (2F4)

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 302

Swiss Prot: P07355

Source: Human Annexin A2 aa 1-200

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.

Conjugation: AbBy Fluor-488

Excitation/ Emission: 499nm/519nm

Size: 100uL

Concentration: Lot Dependent

Applications: WB(1:500-2000)
IHC-P(1:50-200)
IHC-F(1:50-200)
IF(1:50-200)
Flow-Cyt(1:50-100)
ICC/IF(1:50-200)

Predicted Molecular Weight: 38

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.