bsm-54072R [Primary Antibody]
PMP22 Recombinant Antibody
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Host: Rabbit

Target Protein: PMP22

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 5376

Swiss Prot: Q01453

Source: Full length protein

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Store at -20°C for 12 months.

Background:

PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.

Size: 100ul

Concentration: Lot dependent

Cross Reactive Species: Human
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: PC-12 Cells; Probed with PMP22 (1A11) Monoclonal Antibody (bsm-54072R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.