bsm-54156R-Biotin

DATASHEET

Host: Rabbit

Target Protein: CD11b

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 3684

Swiss Prot: P11215

Source: Recombinant Human ITGAM

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100µL

Concentration: 1ug/ul

Applications: WB(WB(1:1000-2000))
IHC-P(IHC-P(1:200-800))
IHC-F(IHC-F(1:200-800))

Predicted Molecular Weight: 170

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.