DATASHEET
Host:
Rabbit
Target Protein:
FABP3
Clonality:
Monoclonal
Isotype:
IgG
Entrez Gene:
2170
Swiss Prot:
P11404
Source:
Recombinant protein within human FABP3 aa 1-100
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Background:
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants.
VALIDATION IMAGES
Paraformaldehyde-fixed and paraffin-embedded Mouse Heart tissue incubated with FABP3 (4C4) Monoclonal Antibody (bsm-54200R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
Lane 1: Rat Heart; Probed with FABP3 (4C4) Monoclonal Antibody (bsm-54200R) at 1:500 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
Paraformaldehyde-fixed and paraffin-embedded Rat Heart tissue incubated with FABP3 (4C4) Monoclonal Antibody (bsm-54200R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.