bsm-54220R [Primary Antibody]
GAB1 Recombinant Antibody
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Host: Rabbit

Target Protein: GAB1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 2549

Swiss Prot: Q13480

Source: Recombinant human GAB1

Purification: purified by Protein A.

Storage Buffer: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

GAB1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway.

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:500-2000)
ICC/IF(1:100-200)

Predicted Molecular Weight: 76 kDa


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with GAB1 monoclonal antibody, unconjugated (bsm-54220R) at 1:500 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.