bsm-54220R-BF405

DATASHEET

Host: Rabbit

Target Protein: GAB1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 2549

Swiss Prot: Q13480

Source: Recombinant human GAB1

Purification: purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

GAB1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway.

Conjugation: AbBy Fluor-405

Excitation/ Emission: 401nm/421nm

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:500-2000)
ICC/IF(1:100-200)

Predicted Molecular Weight: 76 kDa

Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.