DATASHEET
Host:
Rabbit
Target Protein:
RPS19
Clonality:
Recombinant
Isotype:
IgG
Entrez Gene:
6223
Swiss Prot:
P39019
Source:
Full length recombinant protein of RPS19
Purification:
Purified by Protein A.
Storage Buffer:
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C for 12 months.
Background:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS19 is a ribosomal protein that is a component of the 40S subunit. RPS19 belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Conjugation:
Biotin
Excitation/ Emission:
N/A
Size:
100µL
Concentration:
Lot dependent
Applications:
WB(WB(1:500-1000))
IHC-P(IHC-P(1:100-500))
IHC-F(IHC-F(1:100-500))
IP(IP(1:20-50))
Human
Mouse
Rat
For research use only. Not intended for diagnostic or therapeutic use.