bsm-54306R [Primary Antibody]
Cytochrome P450 17A1 Recombinant Antibody
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Cytochrome P450 17A1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 1586

Swiss Prot: P05093

Source: Recombinant human Cytochrome P450 17A1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.

Size: 100ul

Concentration: Lot dependent

Predicted Molecular Weight: 57


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Hui Zhao. et al. Alleviating effects of selenium on fluoride-induced testosterone synthesis disorder and reproduction toxicity in rats. ECOTOX ENVIRON SAFE. 2022 Dec;247:114249Read more>>
  • Qigang Fan. et al. Studying the effect of hyperoside on recovery from cyclophosphamide induced oligoasthenozoospermia. SYST BIOL REPROD MED. 2023 Aug 14Read more>>
VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with Cytochrome P450 17A1 monoclonal antibody, unconjugated (bsm-54306R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.