bsm-54326R [Primary Antibody]
Desmoglein 1 Recombinant Antibody
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Host: Rabbit

Target Protein: Desmoglein 1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 1828

Swiss Prot: Q02413

Source: Recombinant protein within human DSG1 aa 900 to the C-terminus

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Background:

Desmogleins (dsgs) are type I membrane proteins that are important for cell adhesion and are expressed in great abundance at the desmosomes, which are adhesive cell junctions. DSG1 is a component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

Size: 100µL

Concentration: Lot Dependent

Predicted Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Paraformaldehyde-fixed and paraffin-embedded Human Colon Cancer tissue incubated with Desmoglein-1 (5C11) Monoclonal Antibody (bsm-54326R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.


Paraformaldehyde-fixed and paraffin-embedded Human Skin tissue incubated with Desmoglein-1 (5C11) Monoclonal Antibody (bsm-54326R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.


Paraformaldehyde-fixed and paraffin-embedded Human Uterus tissue incubated with Desmoglein-1 (5C11) Monoclonal Antibody (bsm-54326R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.


Paraformaldehyde-fixed and paraffin-embedded Mouse Skin tissue incubated with Desmoglein-1 (5C11) Monoclonal Antibody (bsm-54326R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.