bsm-54386R-Biotin

DATASHEET

Host: Rabbit

Target Protein: P2Y6

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 5031

Swiss Prot: Q15077

Source: Synthetic peptide corresponding to N-terminal human P2Y6.

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

P2Y6 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. Four transcript variants encoding the same isoform have been identified for this gene. Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:300-5000)
IHC-P(1:20-100)
IHC-F(1:200-400)
IP(1:50-200)

Predicted Molecular Weight: 36

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.