bsm-54448R [Primary Antibody]
Cystathionine beta-synthase (1C2) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CBS

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 875

Swiss Prot: P35520

Source: Recombinant protein within human CBS aa 400-550.

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 61


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: 293 Cells; Lane 2: 293 Cells; Lane 3: Human Liver; Probed with Cystathionine beta-synthase (1C2) Monoclonal Antibody (bsm-54448R) at 1:1000, overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.


IF(ICC) staining with Cystathionine beta-synthase (1C2) Monoclonal Antibody (bsm-54448R) at 1:100 in 293T cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100/PBS.