bsm-54491R-Biotin

DATASHEET

Host: Rabbit

Target Protein: ERK1/ERK2 (p-T202/T185)

Modification Site: Thr202+Thr185

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 5594

Swiss Prot: P27361

Source: A synthesized peptide derived from human ERK1 around the phosphorylation site of T202

Purification: purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

The protein encoded by this gene is a member of the MAPkinase family. MAP kinases, also known as extracellularsignal-regulated kinases (ERKs), act in a signaling cascade thatregulates various cellular processes such as proliferation,differentiation, and cell cycle progression in response to avariety of extracellular signals. This kinase is activated byupstream kinases, resulting in its translocation to the nucleuswhere it phosphorylates nuclear targets. Alternatively splicedtranscript variants encoding different protein isoforms have beendescribed. [provided by RefSeq, Jul 2008].

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1mg/ml

Applications: WB(1:500-2000)
IHC-F(1:100-500)
IHC-P(1:100-500)
IF(1:100-500)
Flow-Cyt(1:100-200)
ICC/IF(1:100-200)

Predicted Molecular Weight: 41 kDa

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.