bsm-54527R

DATASHEET

Host: Rabbit

Target Protein: Phospho-MEK1(S218/S222)

Modification Site: Ser218/Ser222

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 5604

Swiss Prot: Q02750

Source: Synthetic phospho-Peptide corresponding to residues surrounding Ser218 and 222 of human MEK1.

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Size: 100uL

Concentration: Lot Dependent

Applications: WB(1:300-5000)
FCM(1:20-100)
IHC-P(1:200-400)
IF(ICC)(1:50-200)
IP(1-2ug)
IHC(1:50-200)

Predicted Molecular Weight: 45

Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.