bsm-54587R

DATASHEET

Host: Rabbit

Target Protein: Phospho-EGFR(Y1068)

Modification Site: Tyr1068

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 1956

Swiss Prot: P00533

Source: Synthetic phospho-Peptide corresponding to residues surrounding Tyr1068 of human EGFR.

Purification: purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:300-5000)
IF(ICC)(1:50-200)
IP(1-2ug)
FCM(1:20-100)

Predicted Molecular Weight: 175

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.