bsm-54668R

DATASHEET

Host: Rabbit

Target Protein: RSK1 p90

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 6195

Swiss Prot: Q15418

Source: Recombinant protein within N-terminal human RSK1 p90.

Purification: purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:300-5000)
IF(ICC)(1:50-200)
IHC(1:50-200)
FCM(1:20-100)
IHC-P(1:200-400)

Predicted Molecular Weight: 83

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.