bsm-54734R

DATASHEET

Host: Rabbit

Target Protein: DOK1

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 1796

Swiss Prot: Q99704

Source: Synthetic Peptide corresponding to Human DOK1.

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 52

Cross Reactive Species: Human
Rat

For research use only. Not intended for diagnostic or therapeutic use.