bsm-56204R-BF350

DATASHEET

Host: Rabbit

Target Protein: IKB alpha

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 4792

Swiss Prot: P25963

Source: KLH conjugated synthetic peptide derived from human NFKBIA

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Conjugation: AbBy Fluor-350

Excitation/ Emission: 346nm/442nm

Size: 100µL

Concentration: Lot dependent

Applications: WB(WB(1:500-2000))
IF(IHC-P)(IF(IHC-P)(1:50-200))
IF(ICC)(IF(ICC)(1:50-200))

Predicted Molecular Weight: 36

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.