bsm-60352M

DATASHEET

Host: Mouse

Target Protein: CYP11A1

Clonality: Recombinant

Isotype: IgG1/Kappa

Entrez Gene: 1583

Swiss Prot: P05108

Source: KLH conjugated synthetic peptide derived from human CYP11A1

Purification: Purified by Protein G.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]

Size: 100uL, 20uL

Concentration: Lot Dependent

Applications: WB(WB=1:500-2000)
IHC-P(IHC-P=1:50-1:100)
IHC-F(ICC=1:50)
IF(IF=1:100-500)
ICC/IF(1:50-100)

Predicted Molecular Weight: 53/57

Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.