bsm-60413M

DATASHEET

Host: Mouse

Target Protein: CD11a

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 3683

Swiss Prot: P20701

Source: KLH conjugated synthetic peptide derived from human CD11a

Purification: Purified by Protein G.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3(intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

Size: 100ul

Concentration: 1mg/ml

Applications: ICC=1:50
IF=1:50

Predicted Molecular Weight: 126

Predicted Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.