bsm-60737R

DATASHEET

Host: Rabbit

Target Protein: CD11b

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 3684

Swiss Prot: P05555

Source: KLH conjugated synthetic peptide derived from human CD11b

Purification: Purified by Protein A.

Storage Buffer: 0.01M PBS.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 125

Cross Reactive Species: Human

Predicted Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.